Wuhan Disel Biotechnology Co., Ltd.

Wuhan Disel Biotechnology Co., Ltd.
Country:  China (Mainland)
Business Type:  Lab/Research institutions
Platinum
Supplier
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  • Ms.Yilia
Ms.Mandy Li
Tel: +86 18672951366
Ms.Yilia
Tel: +86-15926203549
Fax:  +86-27-87001826
City:  Wuhan
Street:  No.6 Fozuling 3rd Road, East Lake High-tech Development Zone, Wuhan City, Hubei Province, China 430000
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bulk supply 475207-59-1/best price Sorafenib tosylate/qualified Sorafenib tosylate

bulk supply 475207-59-1/best price Sorafenib tosylate/qualified Sorafenib tosylate CAS NO.475207-59-1

  • Min.Order: 10 Gram
  • Payment Terms: T/T,MoneyGram,Other
  • Product Details

Keywords

  • best price Sorafenib tosylate
  • qualified Sorafenib tosylate
  • bulk supply 475207-59-1

Quick Details

  • ProName: bulk supply 475207-59-1/best price So...
  • CasNo: 475207-59-1
  • Molecular Formula: C21H16ClF3N4O3.C7H8SO3
  • Appearance: white powder
  • Application:
  • DeliveryTime: 1-3 days
  • PackAge: Aluminum Foil Bag, Drum or Tin
  • Port: Shanghai
  • ProductionCapacity: 200 Metric Ton/Month
  • Purity: 97%+, powder
  • Storage: Dry and cool place
  • Transportation: express, air, sea
  • LimitNum: 10 Gram
  • Trademark: Diselbiotech
  • Alias: Sorafenib
  • Shipping Method: DHL, FEDEX, HKEMS etc.
  • Payment Method: T/T, Western Union, MoneyGram, Paypal,...
  • Shipping Time: Send out within 24 hours after payment
  • Package: Discreet Package & Safe Shipping
  • Origin: China

Superiority

 

Bulk supply  qualified Sorafenib tosylate 475207-59-1 with best price

1) Rich experience


We specialize in this field for many years,our pharmaceutical raw materials exported to Overseas, to 
Europe,Africa,Asia, Americas and other country, and we have got very good feedback from our customers
,and Established long friendly relations of cooperation.


2) Great quality, purity and favorable


Good quality is one of our secret success, welcome order the samples.


3) Safest and fastest delivery

We have Adequate stock,and can arranged within 24 hours when receive the payment.Tracking number 
would be informed quickly after shipment.

We have special way could ship 2kg to 20tons products a time. We offer melting powder into liquid service
.And ship the liquid in special bottles.


4) Good after-sales service
 

Tell the package update ASAP, and will try best solve when customer encountered various problems!

Everything is for customers

Our products and services will focus on the largest customer demand, We hold the greatest enthusiasm 
and sincere cooperation with each customer.

All in all, high quality, best service, security shipping and competitive price are our perpetual pursuance.

 

Details

 
Bulk supply  qualified Sorafenib tosylate 475207-59-1 with best price

 

Quick Detail:

 

Product Name:Sorafenib tosylate
Other Name:Sorafinib mesylate;1-(4-Chloro-3-(trifluoroMethyl)phenyl)-3-(4-((2- (MethylcarbaMoyl)pyridin-4-yl)oxy)phenyl)urea Mono(4- Methylbenzenesulfonate);4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate
CAS:475207-59-1
MF:C21H16ClF3N4O3.C7H8SO3
MW:637.03
Assay:99%min
Appearence:White crystalline powder
Drug category:Anticancer drug
Purpose:This product is mainly used for the treatment of liver and renal cell carcinoma of the clinical anti-cancer agents.
Package:1kg/bag

Function&Usage:

Sorafenib tosylate, also named nexavar, is a small-molecule anticancer compound. It is also a novel oral Raf kinase and a vascular endothelial receptor (VEGFR) inhibitor. It inhibits tumor cell proliferation and tumor angiogenesis [2]. To HepG2 cells (1× 106), the IC50 of sorafenib tosylate is 2.09μg/ml.  
Raf is a mitogen-stimulated protein kinase that functions as a component of the signaling cascade that leads to the stimulation of mitogen-activated protein kinase.
Vascular endothelial (VEGF) is a highly specific mitogen for vascular endothelial cells.
Treatment with nexavar potently inhibited the cell proliferation of MV4-11 cells (FLT3-ITD) in a dose-dependent manner with an IC50 of 0.88 nM. In MV4-11 cells, sorafenib tosylate of a concentration of 100 nM induced 43.6±5.2% of the cells to undergo apoptosis whereas in EOL-1 cells a concentration as low as 10 nM induced 89.29±1.8% of the cells to be apoptotic.
Nude rats at the age of 6 weeks injected with 105 MDA-MB-231 cells were involved. After monotherapy with sorafenib tosylate a significant reduction of the osteolytic lesion volume was observed on days 45 and 55 and of the soft tissue component volume on day 55 in comparison to untreated animals (p < 0.05). Compared to controls, treatment with sorafenib tosylate made bone metastases show significantly decreased values of Amplitude A and kep from day 35 to 55 (Amplitude A: p<0.01; kep p<0.01 on days 35 and 55; p<0.05 on day 45)

COA:

Items of analysis
Specification

Results
Description off-white powder Conforms
Loss on drying NMT 1.0% 0.7%
Water content NMT 0.5% 0.13%
Single impurity NMT0.1% 0.07%
Total impurity NMT 0.5% 0.29%
Purity(HPLC) NLT 99.0% 99.71%
Conclusion Qualified

 

 

How to make an order :


1. Name what your need ( which product , quantity )
2. Full payment would be done once we come to an agreement on all details .
3. Parcel would be shipped out upon receipt of payment .
4. Info about parcel would be offered ( Photo , tracking number )
5. Finally you would get the parcel in 3~7 days .

 

 

Packaging


Sex Enhancer Tadalafil CAS: 171596-29-5



Shipping Method

Sex Enhancer Tadalafil CAS: 171596-29-5

 

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